The biology of the intracranial aneurysm (IA) wall is complex and the precise biomechanical processes leading to IA wall rupture are not yet known. Nowadays, no consensus exists onto the definitions, histological methods and animal models used to characterize IA wall biology. As more and more IAs are incidentally diagnosed and need reliable assessment of their risk of rupture, it becomes evident that a consensus onto definitions and methodology in IA wall research is highly needed.
An effort of harmonisation and standardisation among researchers working on the biology of IAs has been recently initiated by the?Intracranial Aneurysm Dome Working Group (IAD-WG).
Our goals are to:
– Standarize human sample collection, processing and analysis.
– Define animal models that reliably allow to follow intracranial aneurysm initiation, growth and rupture.
If you are already an IAD-WG member, you can upload conference?s videos, articles and protocols on the IAD platform.
If you are not yet a member or need support, please contact IAD management office.